precision health focus

– PMS support
– Hormone balance
– Menopause health support
– Menopause syndrome relief
– Postmenopausal bone health
– Cardiovascular health (CB1R inhibitor)

RenoFlavone™ — a breakthrough fermented soy extract powered by RenoSorb™ postbiotic exo-delivery technology. Standardized with highly water-soluble genistein phosphate, it ensures superior absorption and efficacy, unleashing nature’s restorative power. Among the 12 natural isoflavones, genistein is the most potent phytoestrogen, showing high ERβ/ERα affinity that promotes feminine vitality.

clinical studies

PMS relief 
Randomized, double-blind, placebo-control.
A sample of 120 women (aged 18-40) suffering from primary dysmenorrhea were randomly assigned to either a placebo group or a RenoFlavone™ group, and a 3-month human trial was conducted. The results showed that RenoFlavone™ can relieve PMS symptoms significantly.

Cardiovascular health
Clinical trial with top cardio research institute and hospital.

patents

Patents across United States, Euporean Union, Korea, Japan and Taiwan, with applications focusing on postmenopausal bone health.

100,000x water solubility

Dose: 80mg/100mL
(Left) RenoFlavone™ solution
(Right) Native genistein suspension

370% superior bioavailability

Journal of functional foods 13 (2015) 323–335
https://doi.org/10.1016/j.jff.2015.01.008

TOXOCITY STUDY

This study confirmed the oral toxicity and genotoxicity profile of standardized RenoFlavone™ under good laboratory practice (GLP) conditions.

  • Acute Oral Toxicity Study
  • Ames Test
  • In vivo Mammalian Erythrocyte Micronucleus Test in Mice
  • Repeated Dose 28-Day Oral Toxicity Study

genistein VS isoflavones

Isoflavones are a type of phytoestrogen commonly found in soybeans and soy-derived foods. There are 12 isoflavone isomers and genistein is one of them, which is also recognized as the most bioactive. Several biological effects of genistein have been reported in preclinical studies, including antioxidant, anti-inflammatory, antibacterial, and antiviral activities, as well as effects on angiogenesis, estrogen, and pharmacological activities related to diabetes and lipid metabolism.

WHY GENISTEIN ?

 RenoFlavone™ has been demonstrated to have a high affinity for ERβ.

Upon administration of RenoFlavone™, the mRNA expression of ERα decreased in a dose-dependent manner and the mRNA expression of ERβ increased.